Browsing by Author "Universidad Católica Boliviana “San Pablo” (Santa Cruz, Bolivia)"
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Item A Systematic Review of the Efficacy of Glabellar Botulinum Toxin Injections Compared to Acupuncture in the Treatment of Borderline Personality Disorder(2024) Portillo Saavedra, Natalia; Vargas Sandoval, Ericka; Universidad Católica Boliviana “San Pablo” (Santa Cruz, Bolivia)Borderline personality disorder (BPD) is a complex psychiatric condition characterized by pervasive emotional dysregulation, impulsivity, and difficulties in cognitive control. Patients often exhibit heightened reactivity to negative emotional stimuli, which is associated with increased activity in the amygdala and decreased functionality in the prefrontal cortex during tasks that require inhibition. Given these neurobiological underpinnings, glabellar botulinum toxin (BTX) injections have emerged as a potential treatment option due to their ability to disrupt facial feedback mechanisms that may exacerbate emotional responses.Item Advancing Surgical Approaches for Trigeminal Neuralgia A Meta-Analysis of Endoscopic and Microscopic Microvascular Decompression(2024) Hjeala Varas, Amir; Castillo Sulca, Gabriel; Manrique, Miguel; Carrara Sodre, Katerine; Universidad Católica Boliviana “San Pablo” (Santa Cruz, Bolivia)Item Book Review: Modern Epidemics, From Spanish Flu to COVID-19 by Salvador Macip Maresma(2021) Vargas, Paola A.; Alvarado-Arnez, Lucia Elena; Montellano Duran, Natalia; Universidad Católica Boliviana “San Pablo” (Santa Cruz, Bolivia); Instituto de Investigaciones de Enfermedades Tropicales IIET, Universidad Nacional de Salta UNSA, Salta, Argentina; Coordinación Nacional de Investigación, Universidad Privada Franz Tamayo (Unifranz), La Paz, BoliviaItem Botulinum Toxin as an Adjunct Treatment for Borderline Personality Disorder: A systematic Review of 144 Patients(2024) Cespedes Canavire, Sedrich; Osorio Ortega, Valentina; Universidad Católica Boliviana “San Pablo” (Santa Cruz, Bolivia)Item Caracterización toxinológica del veneno de Bothrops sanctaecrucis(2024) Lobo-López, K.; Universidad Católica Boliviana “San Pablo” (Santa Cruz, Bolivia); Martinez, M.E.; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Instituto Nacional de Medicina; Tropical (INMeT)-ANLIS “Dr. Carlos G Malbrán”. Puerto Iguazú. Misiones. Argentina.; Peichoto, M.E.Item Consequences of inadequate exclusive breastfeeding in Children from latin america: a systematic review(2024) Franco, Sergio; Salazar, Mateo; Vilca, Najhavy; Universidad Católica Boliviana “San Pablo” (Santa Cruz, Bolivia)Introduction: Exclusive breastfeeding is essential for the healthy growth and physical and mental development of your baby. Not breastfeeding or breastfeeding for less than six months increases the risk of the child developing various diseases. Objective: To gather and explain the consequences of not providing exclusive breastfeeding to children in Latin America. Methodology: Scientific articles were searched on the PubMed and Scielo platforms, following the PRISMA method. Specific criteria were used to decide which articles to include or exclude in this study. In total, 13 selected articles were analyzed. Results: The reviewed research shows that insufficient breastfeeding or breastfeeding for less than six months can lead to issues such as developmental and growth delays, overweight and obesity during adolescence, and underweight in childhood. It also indicates a high risk of respiratory diseases such as pneumonia and bronchiolitis, skin problems like allergic dermatitis and atopic dermatitis, iron deficiency anemia, vitamin A deficiency, and severe dehydration. Conclusion: It is important to have new information about the risks of breastfeeding in our society. This helps people understand its significance in preventing diseases and ensuring proper growth for babies.Item Effectiveness and Safety of Probiotics Versus Conventional Antifungal Treatments for Vulvovaginal Candidiasis in Non-Pregnant Women: A Systematic Review(2024) Garcia Agreda, Nicole Quiroga; Moreno Almanza, Mónica C.; Ribera Camacho, Fabio E.; Universidad Católica Boliviana “San Pablo” (Santa Cruz, Bolivia)Background: Vulvovaginal candidiasis (VVC) is a common gynecological condition that can significantly affect the quality of life. Conventional antifungal treatments, while effective, are associated with potential side effects and resistance issues. Probiotics have emerged as a potential alternative or complementary treatment by targeting the vaginal microbiota. This review aims to evaluate whether probiotics, antifungal treatments, or a combination of both are more effective in managing VVC.Item Efficacy of Protein-Based Therapies in Modulating Pathology and Symptoms of Alzheimer’s Disease: A Systematic Review(2024) Rivero Paniagua, Yhazmin; Feeney Camacho, Nicole; Urioste Daza, Jhuliana; Universidad Católica Boliviana “San Pablo” (Santa Cruz, Bolivia)Introduction: Beta-amyloid plaques and tau neurofibrillary tangles disrupt brain function, leading to the progressive cognitive and functional decline characteristic of Alzheimer’s Disease (AD). Current treatments provide only symptomatic relief, failing to address the underlying pathology. Protein-based therapies, including monoclonal antibodies and recombinant protein vaccines, aim to target these pathological mechanisms by clearing beta-amyloid deposits and modulating tau activity. This review evaluates the efficacy of these therapies in improving cognitive and functional outcomes while exploring their limitations and potential. Methods: This systematic review was conducted following PRISMA guidelines and the Cochrane Handbook for Systematic Reviews of Interventions (version 6.3). A comprehensive search of PubMed, Scopus, and Web of Science was performed. Inclusion criteria focused on studies evaluating protein-based therapies targeting amyloid-beta or tau in Alzheimer’s Disease. Data on cognitive and functional outcomes, safety, and biomarkers were extracted and synthesized to identify trends and gaps in the evidence. Results: Eight studies involving 724 participants met the inclusion criteria. Monoclonal antibodies, such as aducanumab, reduced amyloid-beta plaques within 24–48 weeks, but cognitive improvements were inconsistent. Recombinant vaccines, like Lu AF20513, induced strong immune responses in 65–80% of patients, especially with immunostimulant patches. Biomarkers such as alpha-2-macroglobulin showed promise in monitoring treatment efficacy. Adverse events, including mild infusion reactions, were more frequent with antibody therapies, highlighting the need for further optimization. Conclusion: Protein-based therapies show potential in Alzheimer’s Disease treatment by targeting amyloid-beta plaques and tau pathology. Monoclonal antibodies and recombinant vaccines offer promising results in reducing pathological hallmarks and improving immune responses. However, cognitive and functional benefits remain inconsistent, and adverse events are common. Further research is necessary to optimize these therapies, validate biomarkers, and ensure broader clinical applicability.Item Healing with Honey: A Systematic Review of Topical Honey in Burn Wound Management Across 508 Cases(2024) Nazra-Pardo, Alexia; Eguez-Lima, Maria Jose; Camacho, Jeanine; Caballero, Juliana; Universidad Católica Boliviana “San Pablo” (Santa Cruz, Bolivia)Item Metabolic factors associated with kidney stone formation: a sistematic review(2024) Gutiérrez Montaño, Fernanda Ariana; Chavarría Cortez, Fiorella; Nina Masías, Rodrigo; Universidad Católica Boliviana “San Pablo” (Santa Cruz, Bolivia)Kidney stones are a complex and multifactorial disease that affects a large proportion of the world's population. Metabolic factors, such as hypercalciuria, hypocitraturia, hyperoxaluria, and hyperuricosuria, play a crucial role in its development and recurrence. In this systematic review, these factors were analyzed to better understand their influence and contribute to clinical and preventive management. After an exhaustive search in electronic databases and a rigorous screening process, 12 relevant studies were included. The results showed that hypercalciuria affects 50-60% of patients with kidney stones, while hypocitraturia occurs in 60-80% of cases. Furthermore, systemic conditions such as metabolic syndrome and type 2 diabetes were associated with a significant increase in uric acid stone formation, underscoring the relationship between these diseases and lithogenesis. Preventive management based on dietary modifications, such as reducing sodium and animal protein consumption, combined with targeted pharmacological therapies, was shown to be effective in reducing stone recurrence. These findings highlight the importance of a preventive and personalized approach, although they also show the need for future research with more homogeneous methodologies. Identifying and addressing underlying metabolic factors is key to improving patients' quality of life.Item Observatorio de paz y conflictos. Memoria Anual 2022-2023(2023) Universidad Católica Boliviana “San Pablo” (Santa Cruz, Bolivia)Item Reporte de situación conflictos. Diciembre 2022 - enero 2023(2022-12) Universidad Católica Boliviana “San Pablo” (Santa Cruz, Bolivia)Item Reporte de situación. Conflictos - Abril 2023(2023-04) Universidad Católica Boliviana “San Pablo” (Santa Cruz, Bolivia)Item Reporte de situación. Conflictos - Agosto 2023(2023-08) Universidad Católica Boliviana “San Pablo” (Santa Cruz, Bolivia)Item Reporte de situación. Conflictos - Diciembre 2023(2023-12) Universidad Católica Boliviana “San Pablo” (Santa Cruz, Bolivia)Item Reporte de situación. Conflictos - Enero 2023(2023-01) Universidad Católica Boliviana “San Pablo” (Santa Cruz, Bolivia)Item Reporte de situación. Conflictos - Enero 2024(2024-01) Universidad Católica Boliviana “San Pablo” (Santa Cruz, Bolivia)Item Reporte de situación. Conflictos - Febrero 2023(2023-02) Universidad Católica Boliviana “San Pablo” (Santa Cruz, Bolivia)Item Reporte de situación. Conflictos - Julio 2023(2023-07) Universidad Católica Boliviana “San Pablo” (Santa Cruz, Bolivia)Item Reporte de situación. Conflictos - Junio 2023(2023-06) Universidad Católica Boliviana “San Pablo” (Santa Cruz, Bolivia)