Área Salud

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La Unidad Académica Santa Cruz comprometida con el desarrollo científico al servicio de la sociedad boliviana cuenta con dos unidades de investigación en el área de salud: Instituto de investigación en Medicina conformado el año 2012, con más de 6 años de experiencia en proyectos de investigación en el área de enfermedades infecciosas y otros, y la carrea de Odontología, que cuanta con una gran cantidad de producción científica en torno a rehabilitación oral y otras temáticas abordadas desde la clínica odontológica. La participación en investigación de estudiantes de pre grado es fundamental, la misma se ve reflejada y conglomerada en dos sociedades científicas: Sociedad Científica de Estudiantes de Medicina y la Sociedad Científica de estudiantes de Odontología.

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Author: search.filters.author.Camila Choque-Ayala, LuzSubject: search.filters.subject.Hypopituitarism

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    Pituitary Apoplexy and the Current Understanding of Its Management: A Meta-Analysis of 908 Patients
    (World Neurosurgery, 2024) Marin-Castañeda, Luis A.; Gorbachev, Jowah; Lopez-Zepeda, Perla de Teresa; Camila Choque-Ayala, Luz; Shubhangi, Fnu; De Nigris Vasconcellos, Fernando; Pichardo-Rojas, Pavel S.
    Background: Pituitary apoplexy (PA) is characterized by acute hemorrhage or infarction of the pituitary gland. Management can be either conservative or surgical. Evidence favoring either is still limited to observational studies. This meta-analysis evaluates the effectiveness of both approaches on patient outcomes. Methods: A systematic search was performed until February 2024. We included cohort studies of patients with PA. Patients were divided into 2 groups: a conservative management group and a surgery group, including early and late surgery. Outcomes of interest were assessed categorically using risk ratio (RR) and Mantel-Haenszel's random effects model. Results: Of the 273 published articles, 15 cohort studies comprising 908 patients were included. There was no statistically significant difference between groups in recovery of ophthalmoplegia (RR=1.09, confidence interval [CI]=1.00-1.18, P=0.05), visual field (RR=1.09, CI=0.91-1.3, P=0.35), visual acuity (RR=1.05, CI=0.87-1.26, P=0.61), hypopituitarism (RR=1.37, CI=0.81-2.32, P=0.25), and tumor recurrence (RR=0.74, CI=0.34-1.61, P=0.45). This was similar for conservative management versus early surgery in recovery of visual field (RR=0.92, CI=0.62-1.37, P=0.68), visual acuity (RR=1.01, CI=0.81-1.26, P=0.93), and ophthalmoplegia (RR=0.92, CI=0.53-1.61, P=0.77).